The starting line-ups are in from the London Stadium where West Ham welcome Manchester United.
With Mohammed Kudus suspended following his red card against Tottenham, his place is taken in the side by summer signing Carlos Soler, while Alphonse Areola is replaced between the posts.
For the visitors, Bruno Fernandes is available again following his own ban, although Antony misses out through injury.
West Ham: Fabiański; Wan-Bissaka, Mavropanos, Kilman, Emerson; Rodriguez, Alvárez; Soler, Paquetá, Bowen; Antonio.
Manchester United: Onana; Mazraoui, De Ligt, MartĂnez, Dalot; Casemiro, Fernandes, Eriksen; Garnacho, Højlund, Rashford.
The Hammers were beaten 4-1 by Spurs last time out, while United drew in Istanbul in European action on Thursday night.
