West Ham’s Mohammed Kudus begins a three-match suspension after being sent off against Tottenham last weekend.
Forward Niclas Fullkrug is still sidelined with a calf injury.
Manchester United captain Bruno Fernandes is available after being suspended for the midweek draw with Fenerbahce.
Jonny Evans is expected to be fit after missing that game, but Antony looks set to miss out after picking up an injury.
Mason Mount, Harry Maguire, Leny Yoro, Luke Shaw and Kobbie Mainoo are all still out.
Head to head
West Ham
Manchester United
Under Erik ten Hag, Manchester United have lost 17 Premier League away games, which is the same number as they have won while he has been in charge.
Ten Hag’s side have only won two of their last 17 league matches in London (D5, L10), both of which were against Fulham.