Wrexham are waiting for news on the extent of George Evans’ injury after the midfielder was forced off during Tuesday’s defeat at Stevenage.
Evans made his first League One start of the season at the Lamex Stadium, but was forced off early in the second half.
“It’s such a shame for George because he has worked hard to get back into the team,” said Wrexham boss Phil Parkinson.
“He felt something crack. I don’t know what it is, but it is a huge blow.”
Evans’ injury comes after defender Max Cleworth suffered ankle ligament damage in last weekend’s draw at Leyton Orient.
Parkinson said Cleworth’s return date remains uncertain, but said his problem was “not as bad as we first feared”.
“We have had a decent run with injuries so far this season but one or two things have caught up with us a little bit now,” Parkinson added.
“We have to reassess a little bit and look ahead to the weekend.”
Wrexham go in search of a first league win in three games when they host Northampton Town on Saturday.